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ubiquitination 3

Dedifferentiation 1

E3 ubiquitin ligase 1

HDAC inhibitor 1

MYC 1

NOTCH1 1

Phosphoproteome 1

Primary hepatocytes 1

Proteome 1

T cell activation 1

T cell differentiation 1

T cell tolerance 1

T-cell acute lymphoblastic leukemia 1

Ubiquitination 1

chidamide 1

degradation 1

deubiquitinase 1

nucleotide-binding leucine-rich repeat receptor 1

plant immunity 1

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Deubiquitinases as pivotal regulators of T cell functions

Xiao-Dong Yang, Shao-Cong Sun

Frontiers of Medicine 2018, Volume 12, Issue 4,   Pages 451-462 doi: 10.1007/s11684-018-0651-y

Abstract: An emerging mechanism that regulates T cell activation and tolerance is ubiquitination, a reversible

Keywords： deubiquitinase     ubiquitination     T cell activation     T cell differentiation     T cell tolerance    

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Chidamide inhibits the NOTCH1-MYC signaling axis in T-cell acute lymphoblastic leukemia

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 442-458 doi: 10.1007/s11684-021-0877-y

Abstract: down-regulating the level of the intracellular form of NOTCH1 (NICD1) as well as MYC, partly through their ubiquitination

Keywords： T-cell acute lymphoblastic leukemia     HDAC inhibitor     chidamide     NOTCH1     MYC     ubiquitination    

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Regulation of NLR stability in plant immunity

Tao WANG, Jiaxin LI, Qian-Hua SHEN

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 2,   Pages 97-104 doi: 10.15302/J-FASE-2018248

Abstract: In recent years, the ubiquitination-26S proteasome system and the HSP90 chaperones have emerged as having

Keywords： degradation     nucleotide-binding leucine-rich repeat receptor     plant immunity     proteasome     protein stability     ubiquitination    

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Temporal Integrative Omics Reveals an Increase in Nondegradative Ubiquitylation during Primary Hepatocyte Dedifferentiation Article

Zhengyi Jiang, Zeyu Sun, Xiaoxi Ouyang, Yalei Zhao, Menghao Zhou, Baohong Wang, Qirui Li, Linxiao Fan, Sainan Zhang, Lanjuan Li

Engineering 2020, Volume 6, Issue 11,   Pages 1302-1314 doi: 10.1016/j.eng.2020.02.011

Abstract: corresponding WCP indicated that the dedifferentiation of PHCs led to an increase in nondegradative K27 ubiquitinationIn all, 404 proteins with both ubiquitination and phosphorylation were identified to be involved in critical

Keywords： Ubiquitination     Phosphoproteome     Proteome     Dedifferentiation     Primary hepatocytes    

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Title Author Date Type Operation

Deubiquitinases as pivotal regulators of T cell functions

Xiao-Dong Yang, Shao-Cong Sun

Journal Article

Chidamide inhibits the NOTCH1-MYC signaling axis in T-cell acute lymphoblastic leukemia

Journal Article

Regulation of NLR stability in plant immunity

Tao WANG, Jiaxin LI, Qian-Hua SHEN

Journal Article

Temporal Integrative Omics Reveals an Increase in Nondegradative Ubiquitylation during Primary Hepatocyte Dedifferentiation

Zhengyi Jiang, Zeyu Sun, Xiaoxi Ouyang, Yalei Zhao, Menghao Zhou, Baohong Wang, Qirui Li, Linxiao Fan, Sainan Zhang, Lanjuan Li

Journal Article